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1

Thermoresponsive Polymer Micelles as Potential Nanosized Cancerostatics

Laga, Richard, Janoušková, Olga, Ulbrich, Karel, Pola, Robert, Blažková, Jana, Filippov, Sergey K., Etrych, Tomáš, Pechar, Michal

Journal:

Biomacromolecules

Year:

2015

Language:

english

File:

PDF, 2.50 MB

english, 2015

2

In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity

Lynn, Geoffrey M, Laga, Richard, Darrah, Patricia A, Ishizuka, Andrew S, Balaci, Alexandra J, Dulcey, Andrés E, Pechar, Michal, Pola, Robert, Gerner, Michael Y, Yamamoto, Ayako, Buechler, Connor R, Qu

Journal:

Nature Biotechnology

Year:

2015

Language:

english

File:

PDF, 1.93 MB

english, 2015

3

Functionalized hydrogel microparticles prepared by microfluidics and their interaction with tumour marker carbonic anhydrase IX

PittermannovÃ¡, Anna, RuberovÃ¡, Zuzana, LizoÅovÃ¡, Denisa, HubatovÃ¡-VackovÃ¡, Anna, KaÅ¡par, OndÅej, ZadraÅ¾il, AleÅ¡, KrÃ¡l, Vlastimil, Pechar, Michal, Pola, Robert, Bibette, JÃ©rÃ´me, Bremond, N

Journal:

Year:

2020

File:

PDF, 1.49 MB

2020

4

Associative diblock copolymers of poly(ethylene glycol) and coiled-coil peptides

Michal Pechar, Pavla Kopečková, Lisa Joss, Jindřich Kopeček

Journal:

Macromolecular Bioscience

Year:

2002

Language:

english

File:

PDF, 279 KB

english, 2002

5

The Influence of Fusion Sequences on the Thermal Stabilities of Coiled-Coil Proteins

Chunyu Xu, Lisa Joss, Chun Wang, Michal Pechar, Jindřich Kopeček

Journal:

Macromolecular Bioscience

Year:

2002

Language:

english

File:

PDF, 133 KB

english, 2002

6

Macromolecular Drug Delivery. Edited by Mattias Belting.

Journal:

Year:

2009

Language:

english

File:

PDF, 108 KB

english, 2009

7

Modification of pLL/DNA complexes with a multivalent hydrophilic polymer permits folate-mediated targeting in vitro and prolonged plasma circulation in vivo

Christopher M. Ward, Michal Pechar, David Oupicky, Karel Ulbrich, Leonard W. Seymour

Journal:

The Journal of Gene Medicine

Year:

2002

Language:

english

File:

PDF, 304 KB

english, 2002

8

Conjugates of Antibody-Targeted PEG Multiblock Polymers with Doxorubicin in Cancer Therapy

Michal Pechar, Karel Ulbrich, Markéta Jelínková, Blanka Říhová

Journal:

Macromolecular Bioscience

Year:

2003

Language:

english

File:

PDF, 213 KB

english, 2003

9

Thermoresponsive Self-Assembly of Short Elastin-Like Polypentapeptides and Their Poly(ethylene glycol) Derivatives

Michal Pechar, Jiří Brus, Libor Kostka, Čestmír Koňák, Martina Urbanová, Miroslav Šlouf

Journal:

Macromolecular Bioscience

Year:

2007

Language:

english

File:

PDF, 882 KB

english, 2007

10

Biodegradable drug carriers based on poly(ethylene glycol) block copolymers

Michal Pechar, Jiří Strohalm, Karel Ulbrich, Etienne Schacht

Journal:

Macromolecular Chemistry and Physics

Year:

1997

Language:

english

File:

PDF, 614 KB

english, 1997

11

Hydrolytically and Reductively Degradable High-Molecular-Weight Poly(ethylene glycol)s

Alena Braunová, Michal Pechar, Richard Laga, Karel Ulbrich

Journal:

Macromolecular Chemistry and Physics

Year:

2007

Language:

english

File:

PDF, 278 KB

english, 2007

12

CELL AGGREGATION OF THE CYANOBACTERIUM SYNECHOCOCCUS ELONGATUS: ROLE OF THE ELECTRON TRANSPORT CHAIN

Michal Koblížek, Josef Komenda, Jiří Masojídek, Libor Pechar

Journal:

Journal of Phycology

Year:

2000

Language:

english

File:

PDF, 820 KB

english, 2000

13

Spatial and temporal diversity of small shallow waters in river Lužnice floodplain

David Pithart, Radka Pichlová, Michal Bílý, Jaroslav Hrbáček, Kateřina Novotná, Libor Pechar

Journal:

Year:

2007

Language:

english

File:

PDF, 277 KB

english, 2007

14

Multi-component Polymeric System for Tumour Cell-Specific Gene Delivery Using a Universal Bungarotoxin Linker

Ralph A. Willemsen, Michal Pechar, Robert C. Carlisle, Erik Schooten, Robert Pola, Amber J. Thompson, Leonard W. Seymour, Karel Ulbrich

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 510 KB

english, 2010

15

Distribution of aerobic anoxygenic phototrophs in temperate freshwater systems

Michal Mašín, Jiří Nedoma, Libor Pechar, Michal Koblížek

Journal:

Environmental Microbiology

Year:

2008

Language:

english

File:

PDF, 304 KB

english, 2008

16

Synthesis of Biodegradable Polymers for Controlled Drug Release

KAREL ULBRICH, MICHAL PECHAR, JIŘÍ STROHALM, VLADIMÍR ŠUBR, BLANKA ŘÍHOVÁ

Journal:

Annals of the New York Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 492 KB

english, 1997

17

Biodegradable star HPMA polymer conjugates of doxorubicin for passive tumor targeting

Tomáš Etrych, Jiří Strohalm, Petr Chytil, Peter Černoch, Larisa Starovoytova, Michal Pechar, Karel Ulbrich

Journal:

European Journal of Pharmaceutical Sciences

Year:

2011

Language:

english

File:

PDF, 592 KB

english, 2011

18

Effect of physicochemical modification on the biodistribution and tumor accumulation of HPMA copolymers

Twan Lammers, Rainer Kühnlein, Maria Kissel, Vladimir Subr, Tomas Etrych, Robert Pola, Michal Pechar, Karel Ulbrich, Gert Storm, Peter Huber, Peter Peschke

Journal:

Journal of Controlled Release

Year:

2005

Language:

english

File:

PDF, 373 KB

english, 2005

19

Biodegradable high-molecular-weight multiblock polymers based on poly(ethylene glycol) for drug delivery

Alena Braunová, Michal Pechar, Karel Ulbrich

Journal:

Journal of Controlled Release

Year:

2008

Language:

english

File:

PDF, 219 KB

english, 2008

20

Micellization-induced deprotonation of thermoresponsive surfactant CAE-85 — the telechelic carboxylic group derivative of Pluronic P85

Adriana Šturcová, Jiří Dybal, Alena Braunová, Michal Pechar

Journal:

Vibrational Spectroscopy

Year:

2011

Language:

english

File:

PDF, 633 KB

english, 2011

21

Poly(ethylene glycol) Multiblock Copolymer as a Carrier of Anti-Cancer Drug Doxorubicin

Pechar, Michal, Ulbrich, Karel, Šubr, Vladimír, Seymour, Leonard W., Schacht, Etienne H.

Journal:

Bioconjugate Chemistry

Year:

2000

Language:

english

File:

PDF, 213 KB

english, 2000

22

Noninvasive Optical Imaging of Nanomedicine Biodistribution

Kunjachan, Sijumon, Gremse, Felix, Theek, Benjamin, Koczera, Patrick, Pola, Robert, Pechar, Michal, Etrych, Tomas, Ulbrich, Karel, Storm, Gert, Kiessling, Fabian, Lammers, Twan

Journal:

Year:

2013

Language:

english

File:

PDF, 797 KB

english, 2013

23

Tryptophan modification by 2-hydroxy-5-nitrobenzyl bromide studied by MALDI-TOF mass spectrometry

Martin Strohalm, Milan Kodı́ček, Michal Pechar

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 898 KB

english, 2003

24

Polymer Carriers for Anticancer Drugs Targeted to EGF Receptor

Studenovsky, Martin, Pola, Robert, Pechar, Michal, Etrych, Tomas, Ulbrich, Karel, Kovar, Lubomir, Kabesova, Martina, Rihova, Blanka

Journal:

Macromolecular Bioscience

Year:

2012

Language:

english

File:

PDF, 312 KB

english, 2012

25

Pharmaco attributes of dioleoylphosphatidylethanolamine/cholesterylhemisuccinate liposomes containing different types of cleavable lipopolymers

Janny X Zhang, Samuel Zalipsky, Nasreen Mullah, Michal Pechar, Theresa M Allen

Journal:

Pharmacological Research

Year:

2004

Language:

english

File:

PDF, 197 KB

english, 2004

26

Polymeric carriers of drugs for site-specific therapy

Ulbrich, Karel, Pechar, Michal, Strohalm, Jiři, Šubr, Vladimír, říhová, Blanka

Journal:

Macromolecular Symposia

Year:

1997

Language:

english

File:

PDF, 334 KB

english, 1997

27

The coiled coil motif in polymer drug delivery systems

Pechar, Michal, Pola, Robert

Journal:

Biotechnology Advances

Year:

2013

Language:

english

File:

PDF, 692 KB

english, 2013

28

Passive versus Active Tumor Targeting Using RGD- and NGR-Modified Polymeric Nanomedicines

Kunjachan, Sijumon, Pola, Robert, Gremse, Felix, Theek, Benjamin, Ehling, Josef, Moeckel, Diana, Hermanns-Sachweh, Benita, Pechar, Michal, Ulbrich, Karel, Hennink, Wim E., Storm, Gert, Lederle, Wiltru

Journal:

Year:

2014

Language:

english

File:

PDF, 2.10 MB

english, 2014

29

Characterizing EPR-mediated passive drug targeting using contrast-enhanced functional ultrasound imaging

Theek, Benjamin, Gremse, Felix, Kunjachan, Sijumon, Fokong, Stanley, Pola, Robert, Pechar, Michal, Deckers, Roel, Storm, Gert, Ehling, Josef, Kiessling, Fabian, Lammers, Twan

Journal:

Journal of Controlled Release

Year:

2014

Language:

english

File:

PDF, 817 KB

english, 2014

30

Coiled Coil Peptides and Polymer–Peptide Conjugates: Synthesis, Self-Assembly, Characterization and Potential in Drug Delivery Systems

Pechar, Michal, Pola, Robert, Laga, Richard, Braunová, Alena, Filippov, Sergey K., Bogomolova, Anna, Bednárová, Lucie, Vaněk, Ondřej, Ulbrich, Karel

Journal:

Biomacromolecules

Year:

2014

Language:

english

File:

PDF, 2.39 MB

english, 2014

31

Polymer Therapeutics with a Coiled Coil Motif Targeted against Murine BCL1 Leukemia

Pola, Robert, Laga, Richard, Ulbrich, Karel, Sieglová, Irena, Král, Vlastimil, Fábry, Milan, Kabešová, Martina, Kovář, Marek, Pechar, Michal

Journal:

Biomacromolecules

Year:

2013

Language:

english

File:

PDF, 1.61 MB

english, 2013

32

Coiled Coil Peptides as Universal Linkers for the Attachment of Recombinant Proteins to Polymer Therapeutics

Pechar, Michal, Pola, Robert, Laga, Richard, Ulbrich, Karel, Bednárová, Lucie, Maloň, Petr, Sieglová, Irena, Král, Vlastimil, Fábry, Milan, Vaněk, Ondřej

Journal:

Biomacromolecules

Year:

2011

Language:

english

File:

PDF, 2.52 MB

english, 2011

33

Inhibition of Cathepsin K with Lysosomotropic Macromolecular Inhibitors †

Wang, Dong, Pechar, Michal, Li, Weijie, Kopečková, Pavla, Brömme, Dieter, Kopeček, Jindřich

Journal:

Year:

2002

Language:

english

File:

PDF, 222 KB

english, 2002

34

HPMA-copolymer conjugates targeted to tumor endothelium using synthetic oligopeptides

Pola, Robert, Studenovský, Martin, Pechar, Michal, Ulbrich, Karel, Hovorka, Ondřej, Větvička, David, Říhová, Blanka

Journal:

Journal of Drug Targeting

Year:

2009

Language:

english

File:

PDF, 1.54 MB

english, 2009

35

Poly(ethylene glycol)-Based Polymer Carrier of Doxorubicin Degradable by Both Enzymatic and Chemical Hydrolyses

Pechar, Michal, Braunová, Alena, Ulbrich, Karel

Journal:

Collection of Czechoslovak Chemical Communications

Year:

2005

Language:

english

File:

PDF, 138 KB

english, 2005

36

Biodegradable Multiblock Polymers Based on N -(2-Hydroxypropyl)methacrylamide Designed as Drug Carriers for Tumor-Targeted Delivery

Mužíková, Gabriela, Pola, Robert, Laga, Richard, Pechar, Michal

Journal:

Macromolecular Chemistry and Physics

Year:

2016

Language:

english

File:

PDF, 1.63 MB

english, 2016

37

Degradation Behavior of Poly(ethylene glycol) Diblock and Multiblock Polymers with Hydrolytically Degradable Ester Linkages

Braunová, Alena, Pechar, Michal, Ulbrich, Karel

Journal:

Collection of Czechoslovak Chemical Communications

Year:

2004

Language:

english

File:

PDF, 129 KB

english, 2004

38

Targeting distinct myeloid cell populations in vivo using polymers, liposomes and microbubbles

Ergen, Can, Heymann, Felix, Al Rawashdeh, Wa'el, Gremse, Felix, Bartneck, Matthias, Panzer, Ulf, Pola, Robert, Pechar, Michal, Storm, Gert, Mohr, Nicole, Barz, Matthias, Zentel, Rudolf, Kiessling, Fab

Journal:

Year:

2016

Language:

english

File:

PDF, 3.59 MB

english, 2016

39

Tumor-targeted micelle-forming block copolymers for overcoming of multidrug resistance

Braunová, Alena, Kostka, Libor, Sivák, Ladislav, Cuchalová, Lucie, Hvězdová, Zuzana, Laga, Richard, Filippov, Sergey, Černoch, Peter, Pechar, Michal, Janoušková, Olga, Šírová, Milada, Etrych, Tomáš

Journal:

Journal of Controlled Release

Year:

2016

Language:

english

File:

PDF, 1.43 MB

english, 2016

40

Polymer Cancerostatics Targeted with an Antibody Fragment Bound via a Coiled Coil Motif: In Vivo Therapeutic Efficacy against Murine BCL1 Leukemia

Pechar, Michal, Pola, Robert, Janoušková, Olga, Sieglová, Irena, Král, Vlastimil, Fábry, Milan, Tomalová, Barbora, Kovář, Marek

Journal:

Macromolecular Bioscience

Year:

2017

Language:

english

File:

PDF, 1.25 MB

english, 2017

41

Polymeric Conjugates of 9-[2-(Phosphonomethoxy)ethyl]purine with Potential Antiviral and Cytostatic Activity

Pechar, Michal, Braunová, Alena, Šubr, Vladimír, Ulbrich, Karel, Holý, Antonín

Journal:

Collection of Czechoslovak Chemical Communications

Year:

2006

Language:

english

File:

PDF, 100 KB

english, 2006

42

Histidine-rich glycoprotein-induced vascular normalization improves EPR-mediated drug targeting to and into tumors

Theek, Benjamin, Baues, Maike, Gremse, Felix, Pola, Robert, Pechar, Michal, Negwer, Inka, Koynov, Kaloian, Weber, Benjamin, Barz, Matthias, Jahnen-Dechent, Willi, Storm, Gert, Kiessling, Fabian, Lamme

Journal:

Journal of Controlled Release

Year:

2018

Language:

english

File:

PDF, 1.27 MB

english, 2018

43

Antibody-pHPMA functionalised fluorescent silica nanoparticles for colorectal carcinoma targeting

Lizoňová, Denisa, Majerská, Monika, Král, Vlastimil, Pechar, Michal, Pola, Robert, Kovář, Marek, Štěpánek, František

Journal:

Year:

2018

Language:

english

File:

PDF, 1.24 MB

english, 2018

44

POLYMER CANCEROSTATICS TARGETED BY RECOMBINANT ANTIBODY FRAGMENTS TO GD2-POSITIVE TUMOR CELLS

Pola, Robert, Král, Vlastimil, Filippov, Sergey K., Kaberov, Leonid, Etrych, Tomáš, Sieglova, Irena, Sedlacek, Juraj, Fábry, Milan, Pechar, Michal

Journal:

Biomacromolecules

Year:

2018

Language:

english

File:

PDF, 950 KB

english, 2018

45

Microbial food webs in hypertrophic fishponds: Omnivorous ciliate taxa are major protistan bacterivores

Šimek, Karel, Grujčić, Vesna, Nedoma, Jiří, Jezberová, Jitka, Šorf, Michal, Matoušů, Anna, Pechar, Libor, Posch, Thomas, Bruni, Estelle P., Vrba, Jaroslav

Journal:

Limnology and Oceanography

Year:

2019

File:

PDF, 7.88 MB

2019

46

Selective Priming of Tumor Blood Vessels by Radiation Therapy Enhances Nanodrug Delivery

Kunjachan, Sijumon, Kotb, Shady, Pola, Robert, Pechar, Michal, Kumar, Rajiv, Singh, Bijay, Gremse, Felix, Taleeli, Reza, Trichard, Florian, Motto-Ros, Vincent, Sancey, Lucie, Detappe, Alexandre, Yasmi

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 8.57 MB

english, 2019

47

Targeted Polymer-Based Probes for Fluorescence Guided Visualization and Potential Surgery of EGFR-Positive Head-and-Neck Tumors

Pola, Robert, Böhmová, Eliška, Filipová, Marcela, Pechar, Michal, Pankrác, Jan, Větvička, David, Olejár, Tomáš, Kabešová, Martina, Poučková, Pavla, Šefc, Luděk, Zábrodský, Michal, Janoušková, Olga, Bo

Journal:

Year:

2020

File:

PDF, 3.37 MB

2020

48

Polymer Cancerostatics Containing Cell-Penetrating Peptides: Internalization Efficacy Depends on Peptide Type and Spacer Length

Böhmová, Eliška, Pola, Robert, Pechar, Michal, Parnica, Jozef, Machová, Daniela, Janoušková, Olga, Etrych, Tomáš

Journal:

Year:

2020

Language:

english

File:

PDF, 5.55 MB

english, 2020

49

Multimodal and multiscale optical imaging of nanomedicine delivery across the blood-brain barrier upon sonopermeation

May, Jan-Niklas, Golombek, Susanne K., Baues, Maike, Dasgupta, Anshuman, Drude, Natascha, Rix, Anne, Rommel, Dirk, von Stillfried, Saskia, Appold, Lia, Pola, Robert, Pechar, Michal, van Bloois, Louis,

Journal:

Year:

2020

Language:

english

File:

PDF, 1.86 MB

english, 2020

50

Author Correction: Selective Priming of Tumor Blood Vessels by Radiation Therapy Enhances Nanodrug Delivery

Kunjachan, Sijumon, Kotb, Shady, Pola, Robert, Pechar, Michal, Kumar, Rajiv, Singh, Bijay, Gremse, Felix, Taleeli, Reza, Trichard, Florian, Motto-Ros, Vincent, Sancey, Lucie, Detappe, Alexandre, Yasmi

Journal:

Scientific Reports

Year:

2020

File:

PDF, 1.73 MB

2020